Selected Publications

(To view all publications, click here)

Tai, C., Hines, D.J., Choi, H.B. & MacVicar, B.A. (2010). Plasma membrane insertion of TRPC5 channels contributes to the cholinergic plateau potential in hippocampal CA1 pyramidal neurons. Hippocampus (in press).

Kantevari, S., Gordon, G.R.J., MacVicar, B. A. & Ellis-Davies, G.R.C. (2010). A practical guide to the synthesis and use of membrane permeant acetoxymethyl esters of inositol-polyphosphates. Nature Protocols (submitted).

Zhou, N., Rungta, R.L., Feighan, D. & MacVicar, B. A. (2010). A novel form of regenerative glutamate release by NMDA receptors causes spreading depression. Nature Neuroscience (under review).

Choi, H.B., Gordon, R.J., Zhou, N., Tai, C., Ryu, J.K., McLarnon, J.G., Tresguerres, M., Levin, L.R., Buck, J. & MacVicar, B. A. (2010). Metabolic communication between neurons and astrocyte via bicarbonate-responsive soluble adenylyl cyclase. Nature Neuroscience (revisions under review).

Hines, D.J., Choi, H.B., Hines, R.M., Phillips, A. & MacVicar, B. A. (2010). Prevention of LPS-induced microglia activation, cytokine production and sickness behavior with TLR4 receptor interfering peptides. (submitted).

Zhou, N., Gordon, G.R.J., Feighan, D. & MacVicar, B. A. (2010). Transient swelling, acidification, and mitochondrial depolarization occurs in neurons but not astrocytes during spreading depression. Cerbral Cortex.

MacVicar, B. A. & Thompson, R.J. (2009). Microglia processes block the spread of hemmichannels. Trends in Neuroscience: 33(2): 93-102

Hines, D.J., Hines, R. H., Mulligan, S. & MacVicar, B.A. (2009). Microglia processes block the spread of damage in the brain and require functional chloride channels. Glia 57: 1610-1618.

Gordon, G.R.J., Iremonger, K. J., MacVicar, B.A., Bains, J.S. (2009). Discrete astrocyte networks scale multiple excitatory synapses simultaneously.Neuron (under revision).

Thompson, R.J., Jackson, M.F., Olah, M.E., Rungta, R. L., Hines, D.J., Beazely, M.A., MacDonald, J.F. & MacVicar, B.A. (2008). Activation of Pannexin-1 hemmichannels augments aberrant bursting in the hippocampus. Science, 322, 1555-1559. PDF

Gordon G.R. J., Choi, H. B., Ellis-Davies, G.C.R., Rungta, R. L. & MacVicar, B.A.(2008). Brain metabolic state dictates the polarity of astrocyte control over arterioles. Nature 456 (7223): 745-9. PDF

Kisilevsky, A.E., Mulligan, S., Altier, C., Iftinca, M., Varela, D., Tai, C., Hamid, J., Hameed, S., MacVicar, B.A. & Zamponi, G.W. (2008). D1 receptors physically interact with N-type calcium channel complexes to regulate channel trafficking and dendritic calcium entry. Neuron 58, 557–570. PDF

Thompson, R.J., Zhou, N. & MacVicar, B.A. (2006). Ischemia opens neuronal gapjunction hemichannels. Science, 312, 924-927. PDF

Brust, T.B., Cayabyab, F.S., Zhou, N. & MacVicar, B.A. (2006). Mmitogen-activated protein kinase contributes to adenosine A1-receptor-mediated synaptic depression in area CA1 of the rat hippocampus. Journal of Neuroscience, 26,12427-12438. PDF

Tai, C,. Kuzmiski, B.J. & MacVicar, B.A. (2006.) Muscarinic enhancement of R-type calcium currents and spikes in Hippocampal CA1 neurons. Journal of Neuroscience, 26, 6249-58. PDF

Mulligan, S.J.& MacVicar, B.A. (2004.) Calcium transients in astrocyte endfeet cause cerebrovascular constrictions. Nature, 431,195-199. PDF

Armstrong, J.N., Brust, T.B., Lewis, R.G. & MacVicar, B.A. (2002). Activation of presynaptic P2X7 receptors depresses mossy fiber-CA3 synaptic transmission through p38 map kinase. Journal of Neuroscience, 22, 5938-5945. PDF

Horn, T., Wolf, G., Duffy, S. Weiss, S., Keilhoff, G. & MacVicar, B.A. (2002). Nitric Oxide Promotes intracellular Calcium Release From Mitochondria in Striatal Neurons. FASEB Journal 2002, 16, 1611-22. PDF

Panenka, W., Jijon, H., Herx, L.M., Armstrong, J., Feighan, D., Wei, T., Yong, V.W., Ransohoff, R.M., & MacVicar, B.A. (2001). P2X7-like receptor activation in astrocytes increases chemokine MCP-1 expression via MAP kinase. Journal of Neuroscience 21, 7135-7142.

Kuzmiski, B., & MacVicar, B.A. (2001). Cyclic-nucleotide gated channels Contribute to the Cholinergic Plateau Potential in Hippocampal CA1 Pyramidal Neurons. Journal of Neuroscience, 21(22),8707-8714. PDF

MacVicar, B.A. (1999). Intrinsic signal optical imaging in brain slices. In: Imaging: A Laboratory Manual (Eds. R. Yuste, F. Lanni and A. Konnerth); Cold Spring Harbor Laboratory Press. Ch. 34. 15 pages.

Basarsky, T.A, Feighan, D. & MacVicar, B.A. (1999). Glutamate release through volume-activated channels during spreading depression. Journal of Neuroscience, 19, 6439-6445. PDF

Basarsky, T.A, Duffy, S.N., Andrew, R.D. & MacVicar, B.A. (1998). Imaging spreading depression and associated intracellular calcium waves in brain slices. Journal of Neuroscience, 18, 7189-7199.

Crepel, V. Panenka, W., Kelly, M.E.M., MacVicar, B.A. (1998). MAP and tyrosine kinases in the activation of astrocyte volume-activated chloride current. Journal of Neuroscience, 18, 1196-1206.

Duffy, S. & MacVicar, B.A. (1996). In vitro ischemia promotes calcium influx and intracellular calcium release in hippocampal astrocytes. Journal of Neuroscience, 16(1):71-81.

Theodosis, D. & MacVicar, B.A. (1996). Neuron-glia interactions in the hypothalamus and pituitary. Trends in Neuroscience, 19:363-367.

Fraser, D.D. & MacVicar, B.A. (1996). Cholinergic-dependent plateau potential in hippocampal CA1 pyramidal neurons. Journal of Neuroscience, 16:4113-4128. PDF

Fraser, D.D., Hoehn,K. Weiss, S. & MacVicar, B.A. (1993). Arachidonic acid inhibits sodium currents and synaptic transmission in cultured striatal neurons. Neuron, 11:633-644.

Hoehn, K., Watson, T.W.J. & MacVicar, B.A. (1993). Multiple types of calcium channels in acutely isolated rat neostriatal neurons. Journal of Neuroscience, 13, 1244-1257. PDF

Tse, F.W., Duffy, S., Fraser, D. & MacVicar, B.A. (1992). Voltage-activated K+ currents in acutely isolated hippocampal astrocytes. Journal of Neuroscience 12: 1781-1788. PDF

MacVicar, B.A. Hochman, D. (1991). Imaging of synaptically evoked intrinsic optical signals in hippocampal slices. Journal of Neuroscience, 11: 1458-1469.

Fraser, D. & MacVicar, B.A. (1991). Low threshold transient calcium current in rat hippocampal lacunosum-molecular interneurons: Kinetics and modulation by neurotransmitters. Journal of Neuroscience 11: 2812-2820. PDF

MacVicar, B.A.Tse, F.W.Y., Chrighton, S.A. Kettenamnn, H. (1989). GABA-activated hippocampal slices. Journal of Neuroscience, 9:3577-3583.

MacVicar, B.A. (1984). Infrared video microscopy to visualize neurons in the in vitro brain slice preparation. Journal of Neuroscience Methods, 12: 133-139.

MacVicar, B.A. (1984). Voltage-dependent Ca2+ channels in glial cells. Science, 226: 1345-1347.

Andrew, R.D., MacVicar, B.A., Dudek, F.E. & Hatton, G.I. (1981). Dye transfer through gap junctions between neuroendocrine cells of rat hypothalamus. Science 211: 1187-1189.